Best Hotels Near Mayo Clinic Rochester MN

We checked thousands of reviews on and to find the best hotels for your stay
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Alardo Riojas

Updated: 17 January 2024 · 4 min

Nestled in the very heart of the Midwest, Rochester is not just a city with a rich history and vibrant culture; it's also home to the world-renowned Mayo Clinic, a beacon for those seeking premier medical care. This connection has made Rochester a hub for medical tourism and business travel alike, creating a demand for accommodation that caters to a diverse range of needs. Whether you're visiting for healthcare, attending conferences, or exploring the city, finding the right hotel near the Mayo Clinic can significantly enhance your stay.

Understanding the importance of proximity and comfort, especially for those attending the Mayo Clinic, Rochester offers a variety of hotels that cater to patients and their families. From luxury suites that provide a serene retreat to budget-friendly options that focus on convenience and accessibility, there's a place to stay for every type of visitor. These accommodations often feature amenities like shuttle services to the Mayo Clinic, flexible booking policies, and supportive staff to ensure a stress-free stay.

Choosing the perfect hotel near the Mayo Clinic in Rochester involves more than just considering proximity. It's about finding a place that offers peace of mind, essential amenities, and a comfortable base from which to explore the city or attend to medical needs. With the insights and recommendations provided in this article, you'll be equipped to make an informed choice, ensuring your visit to Rochester is both comfortable and conducive to your purpose.
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Our Top 7

(Sorted by rating & number of reviews)

1. La Quinta By Wyndham Rochester Mayo Clinic Area South
2. Doubletree By Hilton Rochester - Mayo Clinic Area
3. Kahler Inn And Suites
4. Hilton Rochester Mayo Clinic Area
5. Days Inn By Wyndham Rochester Downtown
6. Kahler Grand Hotel
7. Rochester Marriott Mayo Clinic Area

Luxury Hotels Near Mayo Clinic Rochester MN

Check Availability

Rochester
Jan 16, 2026 - Jan 17, 2026

La Quinta By Wyndham Rochester Mayo Clinic Area South

7.5

Good

(403 Reviews)

+ 52 photos
La Quinta by Wyndham Rochester is known for its pet-friendly policy, welcoming pets with no additional fee, which is a relief for pet owners looking for convenience and affordability. The hotel offers comfortable rooms and essential amenities, including free Wi-Fi and a complimentary breakfast, ensuring a pleasant stay for all guests. An indoor pool and fitness center provide relaxation and leisure opportunities. The hotel's proximity to the Mayo Clinic, coupled with its acceptance of pets, makes it an excellent choice for those who prioritize the comfort and presence of their furry family members during their visit to Rochester.
Address: 4353 Canal Place Se
Rating: Good 7.5 (403 Reviews)
Rooms: 83
Price: From 89$

Doubletree By Hilton Rochester - Mayo Clinic Area

8.9

Good

(262 Reviews)

+ 187 photos
The DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area warmly welcomes families with its renowned chocolate chip cookie at check-in, setting the tone for a comforting stay. This hotel features spacious rooms and suites that can accommodate families of various sizes, complete with essentials such as cribs on request. An indoor pool and fitness center offer leisure and relaxation opportunities, while the on-site restaurant provides a variety of meals catering to all family members. Its proximity to the Mayo Clinic, with a connected skyway, minimizes the stress of medical visits. The DoubleTree by Hilton notably offers a friendly and supportive staff, enhancing the stay experience for families during their Rochester visit.
Address: 150 South Broadway
Rating: Good 8.9 (262 Reviews)
Rooms: 212
Price: From 142$

Budget-Friendly Hotels Near Mayo Clinic Rochester MN

For travelers visiting the Mayo Clinic in Rochester who seek affordability without sacrificing convenience and comfort, several budget-friendly hotels are available. These accommodations provide essential amenities, such as free Wi-Fi, comfortable rooms, and often, complimentary shuttle services to the Mayo Clinic. Catering to patients, families, and visitors, these hotels understand the importance of a stress-free stay, offering clean, quiet, and accessible lodging options. The emphasis is on providing a hassle-free experience at a value that meets the needs of travelers mindful of their budgets. Staying at one of these hotels means having a practical and comfortable base near the Mayo Clinic, ensuring that medical visits or city explorations are as seamless as possible.

Kahler Inn And Suites

7.0

Good

(1307 Reviews)

+ 75 photos
Kahler Inn and Suites offers an inviting atmosphere for families visiting Rochester, with amenities designed to cater to both children and adults. The hotel's proximity to the Mayo Clinic, just across the street, and connection via pedestrian subway, reduces travel stress for families on medical visits. Spacious rooms and suites equipped with refrigerators and microwaves address the practical needs of family stays. Guests can enjoy the complimentary breakfast, indoor pool, and free Wi-Fi, ensuring entertainment and convenience throughout their stay. Kahler Inn and Suites also acknowledges the diverse needs of its guests with a warm, accommodating staff ready to assist families, making it a preferred choice for comfort and convenience near the Mayo Clinic.
Address: 9 3Rd Avenue Northwest
Rating: Good 7.0 (1307 Reviews)
Rooms: 271
Price: From 109$

Hilton Rochester Mayo Clinic Area

8.9

Good

(202 Reviews)

+ 107 photos
The Hilton Rochester Mayo Clinic Area stands as a beacon of contemporary luxury and convenience. Just steps away from the Mayo Clinic, this hotel is designed to cater to the needs of those seeking wellness and recovery, as well as business and leisure travelers. Each room and suite offers a blend of modern style and ultimate comfort, with panoramic views of the city. Guests can indulge in the on-site restaurant's health-oriented menu, relax in the indoor pool, or rejuvenate in the spa. The Hilton's commitment to service is evident in its range of amenities, including a shuttle service to the Mayo Clinic. This hotel is an excellent choice for travelers looking for a luxurious stay combined with ease of access to medical services.
Address: 10 East Center Street
Rating: Good 8.9 (202 Reviews)
Rooms: 264
Price: From 199$

Family-Friendly Hotels Near Mayo Clinic Rochester MN

Families visiting the Mayo Clinic or exploring Rochester have several hotel options designed with the comfort and convenience of both adults and kids in mind. These establishments typically feature larger rooms or suites, on-site dining with kid-friendly menu options, and amenities like pools and activity centers that can make a stay more enjoyable for younger guests. Understanding the varied needs of families, especially those visiting for medical reasons, these hotels often offer shuttle services to the Mayo Clinic, ensuring hassle-free appointments. Safety, comfort, and convenience are at the forefront, allowing families to focus on their time together, whether for health-related visits or leisure explorations in Rochester.

Days Inn By Wyndham Rochester Downtown

6.2

Good

(426 Reviews)

+ 25 photos
Centrally located and just a short walk from the Mayo Clinic, Days Inn by Wyndham Rochester Downtown is a practical choice for visitors looking for affordability and convenience. This hotel offers clean, comfortable rooms with essential amenities, making it an ideal base for those spending the majority of their time at the clinic or exploring Rochester. Guests can start their day with a complimentary continental breakfast, providing the energy needed for the day ahead. The Days Inn also features free Wi-Fi, allowing guests to stay connected with loved ones or keep up with work. Its proximity to the Mayo Clinic, combined with the hotel's commitment to comfort and value, makes it a favored option for budget-conscious travelers.
Address: 6 1St Ave Nw
Rating: Good 6.2 (426 Reviews)
Rooms: 71
Price: From 105$

Kahler Grand Hotel

7.6

Good

(896 Reviews)

+ 133 photos
As one of the most storied hotels near Mayo Clinic Rochester MN, The Kahler Grand Hotel offers an unmatched blend of historic charm and modern luxury. This hotel stands out not only for its direct access to the Mayo Clinic via a pedestrian skyway but also for its refined elegance and impeccable service. Each room is designed with comfort and convenience in mind, featuring luxurious bedding, spacious layouts, and thoughtful amenities. The Kahler Grand also houses several dining options, from casual to fine dining, allowing guests to savor diverse culinary delights without leaving the comfort of the hotel. For those seeking relaxation, the hotel's spa offers a variety of treatments designed to soothe and rejuvenate. The regal ambiance combined with its proximity to the Mayo Clinic makes The Kahler Grand an ideal choice for those seeking a luxurious stay.
Address: 20 Southwest 2Nd Avenue
Rating: Good 7.6 (896 Reviews)
Rooms: 510
Price: From 76$

Pet-Friendly Hotels Near Mayo Clinic Rochester MN

Pet owners traveling to Rochester for visits to the Mayo Clinic or other purposes need not worry about leaving their furry friends behind, as several hotels offer pet-friendly accommodations. Understanding the comfort that pets can provide, especially during medical visits, these hotels welcome pets with open arms, offering amenities such as pet beds, bowls, and treats. Additional conveniences can include easy access to outdoor areas for walks and pet-sitting services recommendations. These pet-friendly hotels near the Mayo Clinic ensure that the entire family, pets included, can stay together in comfort and ease during their Rochester visit.

Rochester Marriott Mayo Clinic Area

7.4

Good

(134 Reviews)

+ 90 photos
Positioned in the very heart of Rochester provides an elegant and convenient base for visitors. This hotel excels in combining luxury with functionality, offering rooms that are both sophisticated and equipped with modern amenities. Guests will appreciate the warm, attentive service and the hotel's commitment to creating a stress-free environment. The on-site restaurant offers creatively crafted meals that cater to a variety of dietary needs, while the fitness center is perfect for those looking to maintain their wellness routines. Directly connected to the Mayo Clinic via pedestrian subway and skyway, the Marriott ensures guests have easy access to their appointments while enjoying upscale accommodations.
Address: 101 First Avenue Sw
Rating: Good 7.4 (134 Reviews)
Rooms: 202
Price: From 169$